Sporadic cerebral small vessel disease (SVD) is considered to be among the most commonly known neuropathological processes in the brain, hosting a crucial role in stroke, cognitive impairment, and functional loss in elderly subjects. We investigated clinical (neuroimaging and cognitive) biomarkers in the SVD, through a series of analyses from our five studies. Sporadic cerebral SVD is a complex ‘micro-world’ to be globally considered. All the relevant lesion types and SVD neuroimaging burden should be taken into account. The cumulative effects of microangiopathy burden in the brain of patients affected by SVD are crucial. Cognitive rehabilitation could represent a promising approach to prevent vascular dementia or to improve cognitive performances in patients with cerebral SVD. Longitudinal studies may provide more robust information about the progression and prognostic significance of our findings.
- ORCID: 0000-0002-4975-3754
Titolo del libro
Cerebral Small Vessel Disease and Cerebral Amyloid Angiopathy
Sottotitolo del libro
Neuroimaging markers, cognitive features and rehabilitative issues
Autori
Raffaella Valenti
Opera sottoposta a peer review
Numero di pagine
182
Anno di pubblicazione
2018
Copyright
© 2018 Author(s)
Licenza d'uso
Licenza dei metadati
Editore
Firenze University Press
DOI
10.36253/978-88-6453-779-5
ISBN Print
978-88-6453-778-8
eISBN (pdf)
978-88-6453-779-5
eISBN (xml)
978-88-9273-086-1
Collana
Premio Tesi di Dottorato
ISSN della collana
2612-8039
e-ISSN della collana
2612-8020