Monografia

A study on cholinergic signal transduction pathways involved in short term and long term memory formation in the rat hippocampus

Molecular and cellular alterations underlying memory impairments in animal models of neurodegeneration
  • Daniele Lana,

Neurodegenerative processes alter neuronal and glial physiology and cause cognitive and mnemonic impairments. Aim of this PhD thesis is to investigate the involvement of the cholinergic system and the role of mTOR pathway in the mechanisms of memory encoding in the hippocampus and to study the pathophysiological processes at the base of the cognitive impairments in different experimental models of neurodegeneration: in particular normal brain aging, neuroinfiammation and chronic cerebral hypoperfusion. These mechanisms are studied focusing on the morpho-functional alterations in the neuron-astrocytemicroglia triad.

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Acquisto

Daniele Lana

University of Florence, Italy - ORCID: 0000-0002-5193-0019

Daniele Lana was born in Grosseto in 1980. He graduated in Biology in the University of Florence and received his PhD in “Pharmacology, Toxicology and Innovative Treatments” in 2014. His research work is focused on the mechanisms of memory formation and the neurodegenerative processes in the brain.
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  • Anno di pubblicazione: 2015
  • Pagine: 136
  • eISBN: 978-88-6655-941-2
  • Licenza d'uso: CC BY 4.0
  • © 2015 Author(s)
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XML
  • Anno di pubblicazione: 2015
  • eISBN: 978-88-9273-311-4
  • Licenza d'uso: CC BY 4.0
  • © 2015 Author(s)
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  • Anno di pubblicazione: 2015
  • Pagine: 136
  • ISBN: 978-88-6655-940-5
  • Licenza d'uso: CC BY 4.0
  • © 2015 Author(s)
Informazioni bibliografiche

Titolo del libro

A study on cholinergic signal transduction pathways involved in short term and long term memory formation in the rat hippocampus

Sottotitolo del libro

Molecular and cellular alterations underlying memory impairments in animal models of neurodegeneration

Autori

Daniele Lana

Opera sottoposta a peer review

Numero di pagine

136

Anno di pubblicazione

2015

Copyright

© 2015 Author(s)

Licenza d'uso

CC BY 4.0

Licenza dei metadati

CC0 1.0

Editore

Firenze University Press

DOI

10.36253/978-88-6655-941-2

ISBN Print

978-88-6655-940-5

eISBN (pdf)

978-88-6655-941-2

eISBN (xml)

978-88-9273-311-4

Collana

Premio Tesi di Dottorato

ISSN della collana

2612-8039

e-ISSN della collana

2612-8020

718

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