A study on cholinergic signal transduction pathways involved in short term and long term memory formation in the rat hippocampus
Molecular and cellular alterations underlying memory impairments in animal models of neurodegeneration
- Daniele Lana,
Neurodegenerative processes alter neuronal and glial physiology and cause cognitive and mnemonic impairments. Aim of this PhD thesis is to investigate the involvement of the cholinergic system and the role of mTOR pathway in the mechanisms of memory encoding in the hippocampus and to study the pathophysiological processes at the base of the cognitive impairments in different experimental models of neurodegeneration: in particular normal brain aging, neuroinfiammation and chronic cerebral hypoperfusion. These mechanisms are studied focusing on the morpho-functional alterations in the neuron-astrocytemicroglia triad.
- DOI: 10.36253/978-88-6655-941-2
- Series: Premio Tesi di Dottorato
- Scientific Board
- Language: English
- Subjects: Medicine
University of Florence, Italy - ORCID: 0000-0002-5193-0019
- Publication Year: 2015
- Pages: 136
- eISBN: 978-88-6655-941-2
- Content License: CC BY 4.0
- © 2015 Author(s)
- Publication Year: 2015
- Pages: 136
- ISBN: 978-88-6655-940-5
- Content License: CC BY 4.0
- © 2015 Author(s)
Bibliographic Information
Book Title
A study on cholinergic signal transduction pathways involved in short term and long term memory formation in the rat hippocampus
Book Subtitle
Molecular and cellular alterations underlying memory impairments in animal models of neurodegeneration
Authors
Daniele Lana
Peer Reviewed
Number of Pages
136
Publication Year
2015
Copyright Information
© 2015 Author(s)
Content License
Metadata License
Publisher Name
Firenze University Press
DOI
10.36253/978-88-6655-941-2
ISBN Print
978-88-6655-940-5
eISBN (pdf)
978-88-6655-941-2
eISBN (xml)
978-88-9273-311-4
Series Title
Premio Tesi di Dottorato
Series ISSN
2612-8039
Series E-ISSN
2612-8020
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