Religion is undoubtedly the most important cultural phenomenon in world history. It was ubiquitous in medieval and early modern daily life. In all ages and cultures, it has been affected by the economy; on the other hand it has had a profound influence not only on theories, but also on practice, custom, regulation, consumption, tools and in general on the whole economic organization. Even the migratory flows, that produced significant effects and transformations on the European economic system, have been often linked to religion-related issues. The volume that collects the proceedings of the Datinian Study Week investigates through 44 scientific contributions this dynamic and complex relationship, which involved the three main European religions: Christianity, Judaism and Islam, but also the particular experiences within each confession. In fact, they had, in different contexts, different interpretations and divergent dogmatic and doctrinal expressions, which led to significant differences in the evolution of European and Mediterranean economic instruments and relations, starting from the beginning of the second millennium.