Monografia

Purines as Transmitter Molecules: Electrophysiological Studies on Purinergic Signalling in Different Cell Systems

  • Elisabetta Coppi,

Purinergic nucleotides and nucleosides (ATP, ADP, AMP and adenosine) are essential intracellular metabolites involved in a number of cellular processes, from energy supply to protein phosphorylation. However, in the last years, several studies demonstrated their involvement in cell signalling by the activation of specific membrane receptors (P1 and P2) and their role as neurotransmitters began to be investigated. The present work was aimed to clarify the effects of purinergic neurotransmission in different cell systems by using electrophysiological techniques. Relevant results of this research include the observation that P1 and P2 receptors play a deleterious role during "in vitro" ischemia in the rat brain, and the first demonstration of P2 receptor expression and function in a line of adult human mesenchymal stem cells.

  • Parole chiave:
  • Chimica,
  • Chimica inorganica,
  • Fisiologia,
  • Metabolismo,
  • Acidi nucleici,
  • Open Access,
+ Show more
Acquisto

Elisabetta Coppi

University of Florence, Italy - ORCID: 0000-0003-4434-5919

Elisabetta Coppi in 2003 graduated in Biological Science with an experimental thesis. In April 2007 she get the PhD graduation in Pharmacology and Toxicology in the University of Florence and at present she works as a post-doctoral researcher on a project entitled "Study of the neurotransmission in monoaminergic nuclei and hippocampus from rodens in physiological conditions and during the treatment with antidepressant, ansiolytic and psychotropic drugs and/or amphetamine derivatives".
PDF
  • Anno di pubblicazione: 2008
  • Pagine: 192
  • eISBN: 978-88-8453-905-2
  • Licenza d'uso: CC BY-ND 3.0 IT
  • © 2008 Author(s)
Download PDF
XML
  • Anno di pubblicazione: 2008
  • eISBN: 978-88-9273-789-1
  • Licenza d'uso: CC BY-ND 3.0 IT
  • © 2008 Author(s)
Download XML
PRINT
  • Anno di pubblicazione: 2008
  • Pagine: 192
Informazioni bibliografiche

Titolo del libro

Purines as Transmitter Molecules: Electrophysiological Studies on Purinergic Signalling in Different Cell Systems

Autori

Elisabetta Coppi

Opera sottoposta a peer review

Numero di pagine

192

Anno di pubblicazione

2008

Copyright

© 2008 Author(s)

Licenza d'uso

CC BY-ND 3.0 IT

Licenza dei metadati

CC0 1.0

Editore

Firenze University Press

DOI

10.36253/978-88-8453-905-2

ISBN Print

978-88-8453-904-5

eISBN (pdf)

978-88-8453-905-2

eISBN (xml)

978-88-9273-789-1

Collana

Premio Tesi di Dottorato

ISSN della collana

2612-8039

e-ISSN della collana

2612-8020

News ed Eventi
News
Premio Tesi di Dottorato - EDIZIONE 2010
  • 18/06/2010
584

Download dei libri

914

Visualizzazioni

Cerca in questo libro
Salva la citazione
Libri consigliati

1.685

Volumi pubblicati

1.383

Libri in accesso aperto

in catalogo

2.567

Capitoli di Libri

4.133.292

Download dei libri

4.947

Autori

da 1047 Istituzioni e centri di ricerca

di 66 Nazioni

69

scientific boards

da 368 Istituzioni e centri di ricerca

di 43 Nazioni

1.299

I referee

da 393 Istituzioni e centri di ricerca

di 38 Nazioni