Monograph

Molecular imaging in Parkinson's disease

  • Cristina Polito,

The present work explores brain functional changes in drug-naïve Parkinson's disease (PD) patients by means of molecular imaging techniques. Thirty-one consecutive drug-naïve PD patients from the Neurological Clinic of the University of Flor-ence underwent clinical assessment, neuropsychological assessment, MRI, [123I]FP-CIT SPECT, [18F]FDG PET.
First, [18F]FDG-PET was employed to identify in drug-naïve PD patients brain metabolic alteration uniquely related to disease process and not modulated by anti-parkinsonian therapeutic intervention. Second, [18F]FDG-PET and [123I]FP-CIT SPECT were employed together to explore the early functional changes in brain function related to dopaminergic depletion in the putamen and in the caudate nucleus.

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Cristina Polito

University of Florence, Italy - ORCID: 0000-0001-7509-5575

Cristina Polito, Psychologist, Ph.D. in Neuroscience. Main interest in neurodegenerative diseases. Post-doctoral position at the Università di Firenze, Dipartimento di scienze Neurologiche e Psichiatriche, Dipartimento di Fisiopatologia Clinica.
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  • Publication Year: 2011
  • Pages: 68
  • eISBN: 978-88-6655-041-9
  • Content License: CC BY-ND 3.0 IT
  • © 2011 Author(s)

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  • Publication Year: 2011
  • eISBN: 978-88-9273-645-0
  • Content License: CC BY-ND 3.0 IT
  • © 2011 Author(s)

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  • Publication Year: 2011
  • Pages: 68
  • eISBN: 978-88-6655-037-2
  • Content License: CC BY-ND 3.0 IT
  • © 2011 Author(s)

Bibliographic Information

Book Title

Molecular imaging in Parkinson's disease

Authors

Cristina Polito

Peer Reviewed

Number of Pages

68

Publication Year

2011

Copyright Information

© 2011 Author(s)

Content License

CC BY-ND 3.0 IT

Metadata License

CC0 1.0

Publisher Name

Firenze University Press

DOI

10.36253/978-88-6655-041-9

ISBN Print

978-88-6655-037-2

eISBN (pdf)

978-88-6655-041-9

eISBN (xml)

978-88-9273-645-0

Series Title

Premio Tesi di Dottorato

Series Issn ISSN

2612-8039

Series E-Issn

2612-8020

311

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