Folding and aggregation studies in the acylphosphatase-like family
- Francesco Bemporad,
Folding and misfolding of proteins are considered two sides of the same coin. The delicate equilibrium existing between these two processes is crucial for any living organism and its alterations can lead to the onset of several tremendous diseases, such as Alzheimer's and Parkinson's disease. The attainment of a profound knowledge of folding/misfolding processes is a key step to understand how life works and for discovering new therapies to these diseases. In this work the author shows that proteins can display enzymatic activity even in the absence of a compact three-dimensional structure, with important implications for the study of protein enzymes. Furthermore, the author investigates the formation of protein aggregates similar to those observed in patients of amyloid-related diseases.
- Keywords:
- Medicina,
- Biologia,
- Chimica,
- DOI: 10.36253/978-88-8453-946-5
- Series: Premio Tesi di Dottorato
- Scientific Board
- Language: English
- Subjects: Medicine
University of Florence, Italy - ORCID: 0000-0002-0643-6249
- Publication Year: 2009
- Pages: 126
- eISBN: 978-88-8453-946-5
- Content License: CC BY-NC-ND 3.0 IT
- © 2009 Author(s)
- Publication Year: 2009
- eISBN: 978-88-9273-768-6
- Content License: CC BY-NC-ND 3.0 IT
- © 2009 Author(s)
- Publication Year: 2009
- Pages: 126
- ISBN: 978-88-8453-945-8
- Content License: CC BY-NC-ND 3.0 IT
- © 2009 Author(s)
Bibliographic Information
Book Title
Folding and aggregation studies in the acylphosphatase-like family
Authors
Francesco Bemporad
Peer Reviewed
Number of Pages
126
Publication Year
2009
Copyright Information
© 2009 Author(s)
Content License
Metadata License
Publisher Name
Firenze University Press
DOI
10.36253/978-88-8453-946-5
ISBN Print
978-88-8453-945-8
eISBN (pdf)
978-88-8453-946-5
eISBN (xml)
978-88-9273-768-6
Series Title
Premio Tesi di Dottorato
Series ISSN
2612-8039
Series E-ISSN
2612-8020
News and Events
Premio Tesi di Dottorato - edizione 2009
- 25/01/2010 |
- Aula Magna Università di Firenze – p.zza San Marco 4 Firenze
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